Lady Gaga of “American Horror Story: Hotel” and Jamie Lee Curtis of “Scream Queens” are arguably some of the most famous new faces on TV. But fame isn’t all it’s cracked up to be — at least not for Curtis, who told Gaga during their conversation for the fourth season of Variety and PBS’ “Actors on Actors” series, that it’s “isolating.”

The duo also discussed Curtis’ blockbuster film “True Lies,” “The Jinx” and working with “American Horror Story” creator Ryan Murphy.

The two-part fourth-season premiere of “Variety Studio: Actors on Actors,” presented by Shopbop/East Dane, airs June 12 and June 19 on PBS SoCal.