In the upcoming Jacques Audiard-helmed crime-drama “The Sisters Brothers,” Joaquin Phoenix and John C. Reilly are brothers and assassins who find themselves on a perilous journey through the Northwest.

“Nightcrawler” alums Jake Gyllenhaal and Riz Ahmed also star in the Western. During the Toronto Film Festival, Reilly and Ahmed stopped by the Variety Studio, presented by AT&T, to discuss how they wanted to show a more accurate portrayal of the West in the film.

“We were actually trying to avoid some of the cliches that famous Westerns have and Jacques was the perfect person,” said Reilly. “Because he loves subverting people’s assumptions of things, whether it’s in a scene or the larger world.”