Introduction

To celebrate the 50th anniversary of the iconic sci-fi show take a look at some of the guest stars the show brought in who ended up being household names.
To celebrate the 50th anniversary of the iconic sci-fi show take a look at some of the guest stars the show brought in who ended up being household names.
Long before Tom Hardy starred opposite Leonardo DiCaprio in films like “Inception” and “The Revenant,” he played Shinzon, the villain in “Star Trek: Nemesis.” Shinzon was a clone of Patrick Stewart’s Jean-Luc Picard.
An appearance on “Star Trek: Voyager” was one of the first non-wrestling roles that Dwayne Johnson took. He played the Pendari Champion who defeated Jeri Ryan’s Seven of Nine in combat.
Before playing the fabulous Samantha Jones on “Sex and the City,” Kim Cattrall donned prosthetic ears to play the Vulcan helmsman Valeris in “Star Trek VI: The Undiscovered Country.”
“Spider-Man” and “Fargo” star Kirsten Dunst appeared in “Star Trek: The Next Generation” at the age of 11. She played Hedril, a young member of a telepathic alien race known as the Cairn.
Most well-known for his role as Emmett “Doc” Brown in the “Back to the Future” trilogy, Christopher Lloyd also played the Klingon Commander Kruge in “Star Trek III: The Search for Spock.”
Christian Slater played an unnamed officer in “Star Trek VI: The Undiscovered Country.” Slater is known for “Interview with a Vampire,” “True Romance,” and most recently “Mr. Robot.”
Comedian Sarah Silverman appeared in an episode of “Star Trek: Voyager” where the crew was sent back in time on Earth. Silverman played a scientist based in Los Angeles.
“Seinfeld’s” Jason Alexander also appeared on “Star Trek: Voyager” as Kurros, a member of a group of scholars who traversed the galaxy looking for employment in solving problems.
“Desperate Housewives” and “Lois and Clark” star Teri Hatcher appeared in an episode of “Star Trek: The Next Generation” as a Starfleet lieutenant.
Frasier himself, Kelsey Grammer, appeared in an episode of “Star Trek: The Next Generation” as the captain of ship caught in a time loop and on a collision course with the Enterprise.
Kelsey Grammer’s TV wife — Bebe Neuwirth — also appeared on “The Next Generation.” She played an alien nurse who promised to help Commander Riker escape confinement in exchange for sexual favors.
Another “Cheers” star — Kirstie Alley — played Saavik in “Star Trek II: The Wrath of Khan.”
Jeffrey Dean Morgan is familiar with playing the villian. Before he was cast as baseball bat-wielding Negan in “The Walking Dead,” Morgan played a Xindi-Reptillian tasked with destroying Earth in “Star Trek: Enterprise.”
Iggy Pop, the punk legend who created “The Passenger,” “Search and Destroy” and more, appeared in “Star Trek: Deep Space 9” as a Vorta negotiator named Yelgrun.
Eight years before Famke Janssen and Patrick Stewart would star together in “X-Men” the actress appeared in an episode of “Star Trek: The Next Generation” where she seduced Stewart’s Jean-Luc Picard.
Based on the sheer number of references in his shows “Family Guy,” “American Dad” and films “Ted” and “Ted 2,” it’s evident that Seth Macfarlane is a Trekkie. Happily, Macfarlane was able to appear in two episodes of “Star Trek: Enterprise” as a Starfleet engineer.
“NewsRadio” alum Andy Dick was in an episode of “Star Trek: Voyager” as a holographic ship doctor.
“Heat” and “Divergent” star Ashley Judd guest starred in two episode of “Star Trek: The Next Generation.” Judd also had her first on-screen kiss on the show with Wil Wheaton’s Wesley Crusher.
Before Terry O’Quinn headed to the island in “Lost” as John Locke, he appeared in “Star Trek: The Next Generation” as an admiral and friend of William Riker.
Another “Lost” alum appeared in “Star Trek.” Daniel Dae Kim, who would go on to play Jin in “Lost,” appeared in an episode of “Star Trek: Voyager” and later as a different character in three episodes of “Star Trek: Enterprise.”
“Eraser” and “Shaft” star Vanessa Williams guest starred on “Star Trek: Deep Space 9” as Arandis, an inhabitant of a pleasure planet.
Theoretical physicist Stephen Hawking appeared in an episode of “Star Trek: The Next Generation” as a holographic version of himself playing poker with Albert Einstein and Isaac Newton.
“Parks and Recreation” and “Step Brothers” star Adam Scott had a blink and you’ll miss it role in “Star Trek: First Contact” as a crew member.
“That 70s Show’s” Kurtwood Smith has appeared in numerous Star Trek projects. He was an Efrosian Federation president in “Star Trek VI: Undiscovered Country,” as the predecessor to Odo in an episode of “Star Trek: Deep Space 9,” and as Annorax in two episodes of “Star Trek: Voyager.”
Mick Fleetwood, of Fleetwood Mac fame, underwent heavy make-up for a role in “Star Trek: The Next Generation” as an Antedean dignitary.
Tom Bergeron, host of both “Dancing with the Stars” and “America’s Funniest Home Videos,” appeared in two separate episodes of “Star Trek: Enterprise.”
“Star Trek IV: The Voyage Home” featured a cameo from Trekkie and The Go-Go’s vocalist Jane Wiedlin.
The former “Entertainment Tonight” host and musician played a Klingon hologram who helped Worf complete his second right of ascension ceremony.
Tom Morello, of Rage Against the Machine and Audioslave fame, appeared twice in the “Star Trek” universe. He had a small cameo in the “Star Trek: Insurrection” and then appeared in an episode of “Star Trek: Voyager.”
“L.A. Law” and “Psych” alum Corbin Bernsen played a member of the omnipotent Q Continuum in an episode of “Star Trek: The Next Generation.”
“Fresh Prince of Bel-Air’s” Uncle Phil, James Avery, played a Klingon general in an episode of “Star Trek: Enterprise.”
Paul Sorvino, who starred in “Goodfellas,” “Romeo + Juliet” and the father of Mira Sorvino, played Worf’s foster brother in an episode of “Star Trek: The Next Generation.”
“Twilight” star and “Revolution” alum Billy Burke made his first TV appearance on an episode of “Star Trek: Deep Space 9” as a Cardassian soldier.
Perhaps the most powerful guest star to appear in the show, King of Jordan Abdullah II ibn al Hussein had a non-speaking role in “Star Trek: Voyager” while he was still a prince.
Best known for playing a lecherous lawyer on “Night Court,” John Larroquette played the Klingon Maltz in “Star Trek III: The Search for Spock.”
Before “Arrow” and “Marvel: Agents of S.H.I.E.L.D,” Neal McDonough played Lt. Hawk in “Star Trek: First Contact.”