A24 acquired U.S. rights to Nicole Holofcener’s new comedy “Beth & Don,” starring Julia Louis-Dreyfus, at AFM.

Last week, Variety exclusively revealed that Louis-Dreyfus and Holofcener would reunite for the movie after their 2013 hit “Enough Said.”

Louis-Dreyfus stars as Beth, a New York novelist in an unbelievably happy marriage to Don, who loves her and supports her in every way. According to the official longline, the film’s plot kicks off when, one day, Beth overhears Don admitting that he hasn’t liked her writing in years and it threatens to undo all that’s good in their lives. Written and directed by Holofcener, “Beth & Don” is set to begin shooting in early 2022.

The 11-time Emmy winner will also produce the film alongside Likely Story’s Anthony Bregman and Stefanie Azpiazu, who produced “Enough Said” and are longtime collaborators with both Holofcener and Louis-Dreyfus.

UTA Independent Film Group negotiated the sale of the U.S. rights to A24, which will release the project theatrically. Film Nation is handling all international sales.

The acquisiton also marks Louis-Dreyfus’s second film with A24, following “Tuesday,” the directorial debut from Dainah Oniunias-Pusic, which recently wrapped production. Best known for conquering comedic television with her award-winning work on “Seinfeld” and “The New Adventures of Old Christine” and “Veep,” Louis-Dreyfus is now taking the Marvel Cinematic Universe, appearing as Valentina Allegra de Fontaine in both ”The Falcon and the Winter Soldier” and ”Black Widow.”

Holofcener has written and directed six films including “Friends With Money,” “Lovely and Amazing” and “Walking and Talking.” Most recently, she co-wrote the screenplay for “The Last Duel,” a historical epic directed by Ridley Scott, and is in pre-production for a new film that she’s written and will direct.

Holofcener is repped by UTA and attorney Alan Wertheimer. Louis-Dreyfus is repped by CAA, ID and attorney Jonathan West. Likely Story is repped by Craig Emanuel at Paul Hastings.