Tom Holland takes on the role of an addict forced to rob banks to pay off his debt in trailer for “Cherry,” which dropped Thursday.

The film is directed by Anthony and Joe Russo, who are from Cleveland, Ohio — the same place where Holland’s character is from. With a serious theme of drug addiction at the center of the crime drama, the Russos hope to shine a light on the impact of the opioid crisis.

“It’s a very emotionally important movie for us. That part of the country has been designated ground zero for the opioid crisis,” Joe Russo said in a Q&A with Inverse. “We’ve had a lot of people we were very close to die because of the crisis. We felt that it was a story that needed to be told and the luxury of coming off of movies like ‘Infinity War’ and ‘Endgame’ is that you can get complicated subject matter made in a difficult market for content like that.”

In Holland’s first roles working with the Russo Brothers on “Captain America: Civil War” and the most recent two “Avengers” movies, he donned the persona of an innocent, fun-loving Spider-Man. In “Cherry,” the actor takes on a much more serious role for the main character.

“It’s a story about the opioid crisis that involves the Iraq war, PTSD, heroin addiction, Oxycontin addiction, bank robbing,” Anthony Russo said. “It’s a very intense film and Tom Holland is absolutely bringing it every day. We’re so impressed with his performance in this movie. It will be a very intense film.”

Starring alongside Holland are Ciara Bravo, Jack Reynor, Kelli Burglund, Jack Reynor, Forrest Goodluck, Jeff Wahlberg, Michael Gandolfini, Kyle Harvey and Thomas Lennon.

“Cherry” is produced by Anthony Russo, Joe Russo, Mike Larocca, Chris Castaldi, Jonathan Gray and Matthew Rhodes. Executive producers are Todd Makurath, Jake Aust, Kristy Maurer Grisham and Judd Payne.

Watch the full trailer below.