The reality star made the announcement on Tuesday morning, writing on her Instagram, “What a journey this has been. I have laughed and cried and tried to Make it Nice…But all things must come to an end.”
Medley has part of the hit reality show for six seasons, becoming a fan-favorite and garnering a cult following of fans. She is known for her over-the-top on-screen behavior and memorable catchphrases like, “Make it nice.”
She joined as a full-time cast member in the seventh season. The show, which has been on since 2008, is currently airing its 12th season.
Though there is the old adage that no one ever actually quits “The Real Housewives,” a source close to the network says it was a “mutual decision” and that “all agreed she needed a break.”
Bravo did not immediately respond to Variety’s request for comment.
The king of Bravo, Andy Cohen, commented on Medley’s Instagram announcement on Tuesday, writing, “What a ride. Unforgettable.”
Season 12 has featured a regular cast of Medley, Luann de Lesseps, Ramona Singer, Sonja Morgan, Tinsley Mortimer and Leah McSweeney, who is the newest member to join the show at the beginning of the current season.
Mortimer also will not be returning next season, she announced earlier this summer, meaning the thirteenth season will have a void of two core cast members.
The “Real Housewives” franchise has seen many cast shakeups over the years. Most notably, the New York installment, recently saw reality star-turned-businesswoman Bethenny Frankel step away from the series, after Variety exclusively broke the news, ahead of the most recent season.
On Instagram, Medley showed gratitude for the network and her cast when announcing her departure.
“This was a great outlet for me to heal when my late husband Richard passed away,” Medley wrote. “I have met so many interesting people and learned so much about myself, about life and about women along the way…Thank you to Bravo and NBC for the incredible ride and to my cast mates for constant stimulation and entertainment. I wish you all health, happiness and success.”
Kate Aurthur contributed to this story.