Annaleigh Ashford will star in the CBS multi-camera comedy pilot “B Positive.”

In the show, faced with finding a kidney donor, newly divorced dad Drew is at the end of his rope when he runs into Gina (Ashford), a rough-around-the edges woman from his past who volunteers her own. Together they form an unlikely bond and begin a journey that will change both of their lives.

Gina is further described as a working-class woman who is larger than life in every sense — most importantly, her heart. She lives in her mother’s basement, drives a senior citizen van for a living, and makes rash decisions, including giving Drew her kidney.

Ashford will film the “B Positive” pilot concurrently with the upcoming season of “American Crime Story” at FX, which will focus on the impeachment of President Bill Clinton. Ashford is set to play Paula Jones. She previously appeared in Season 2 of “ACS.” Her other TV credits include “Masters of Sex,” “Younger,” and Fox’s staging of “The Rocky Horror Picture Show.” She is also a noted stage actress and won the Tony Award for her performance in “You Can’t Take it with You” and was previously nominated for her role in “Kinky Boots.”

She is repped by ICM, Beth Rosner Management and Schreck Rose.

“B Positive” hails from writer and executive producer Marco Pennette. Chuck Lorre will executive produce via Chuck Lorre Productions Inc. Pennette already works with Lorre on the Anna Faris and Allison Janney CBS sitcom “Mom.” Warner Bros. Television, where Lorre is under a rich overall deal, will produce.