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Winona Ryder, John Turturro, Anthony Boyle, Zoe Kazan, Morgan Spector, Caleb Malis, and Azhy Robertson will lead the ensemble cast of HBO’s miniseries “Plot Against America” from David Simon.

Simon and Ed Burns will executive produce the show along with Joe Roth, Nina K. Noble, Megan Ellison, Sue Naegle, Susan Goldberg, and Jeff Kirschenbaum. The project will be co-exec produced by Dennis Stratton and the late Philip Roth.

Based on Roth’s novel, the six-part series will imagine an alternate American history told through the eyes of a working-class Jewish family in New Jersey, as they watch the political rise of Charles Lindbergh — an aviator-hero and xenophobic populist, who becomes president and turns the nation toward fascism.

Boyle is a rising star who won a Tony and Olivier Award for his performance in the hit play “Harry Potter and the Cursed Child.” He can next be seen opposite Nicholas Hoult in Fox Searchlight’s biopic “Tolkien.” He is represented by UTA and Hamilton Hodell.

Ryder will star in Season 3 of “Stranger Things,” which bows this summer. She also has “Destination Wedding,” alongside Keanu Reeves, hitting theaters later this year. She is repped by Gersh and Anonymous Content.

Turturro has strong ties with HBO, most recently appearing in the cabler’s miniseries “The Night Of.” He is repped by ICM Partners.

In addition to her acting roles, Kazan recently wrote the screenplay for Paul Dano’s “Wildlife,” starring Carey Mulligan. She is repped by UTA.