Melissa Leo, Rosie O’Donnell Among Cast Added to Mark Ruffalo’s ‘I Know This Much Is True’

Melissa Leo and Rosie O’Donnell have joined the cast of the HBO limited series “I Know This Much Is True,” along with Archie Panjabi, Imogen Poots, Juliette Lewis, and Kathryn Hahn.

HBO has given a production commitment to the six-episode drama, which stars and is executive produced by Mark Ruffalo. The family drama follows the parallel lives of identical twin brothers in a story of betrayal, sacrifice, and forgiveness, taking place against the backdrop of 20th century America. It is based on the book of the same name by Wally Lamb, who is also serving as an executive producer on the project.

Ruffalo stars as twin brothers Dominick and Thomas Birdsey, with Leo playing Ma (Concettina Ipolita Tempesta Birdsey), Dominick and Thomas’ mother. O’Donnell stars as Lisa Sheffer, a social worker at the Hatch Forensic Institute, where Thomas is staying. Additionally, Panjabi portrays Dr. Patel, Thomas’ newly appointed psychologist; Poots is Joy Hanks, Dominick’s live-in girlfriend; Lewis is Nedra Frank, a self-absorbed grad student hired by Dominick; and Hahn is Dessa Constantine, Dominick’s ex-wife.

Leo won an Oscar and Golden Globe for her performance in “The Fighter,” and received an Academy Award nomination for 2008’s “Frozen River.” She most recently starred in the Showtime dramedy “I’m Dying Up Here.” Leo is repped by Untitled Entertainment and CAA.

O’Donnell is known for appearing on talk series, including “The Rosie O’Donnell Show,” ABC’s “The View,” and “Rosie Radio.” She has also had a prolific career in film and television, with roles in movies like “A League of Their Own” and “Sleepless in Seattle,” and series such as “Will & Grace” and “The Fosters.” Most recently, O’Donnell starred in Showtime’s series “SMILF.” She is repped by WME.

Panjabi’s standout performance on CBS’ “The Good Wife” earned her an Emmy Award and three total nominations. She recently starred in and executive produced the six-part-drama “Next of Kin” in 2018. She is repped by Gersh.

Poots broke through in the film “28 Weeks Later,” and has also appeared in films such as “Jane Eyre,” “A Late Quartet,” and “Filth.” She is repped by CAA, Troika, and Narrative PR.

Lewis earned an Oscar and Golden Globe nomination for her role in Martin Scorsese’s “Cape Fear.” She has starred in critically acclaimed films like “What’s Eating Gilbert Grape,” “From Dusk Till Dawn,” and “August: Osage County.” Lewis is repped by Untitled Entertainment and UTA.

Hahn is a veteran of comedy films and television series, and recently received an Emmy nomination for her performance in Amazon’s “Transparent.” She also lent her voice to Columbia Pictures’ animated feature “Spider-Man: Into the Spider-Verse.” Hahn is repped by Gersh, Lighthouse Management, and Media and Schreck Rose.

I Know This Much Is True” is written, directed, and executive produced by Derek Cianfrance (“Blue Valentine”). Also executive producing are Ben Browning and Glen Basner for FilmNation Entertainment, Gregg Fienberg, Anya Epstein, and Lynette Howell Taylor. It is co-executive produced by Jamie Patricof.

Popular on Variety

More TV

  • Screen writer Beau WillimonMary Queen of

    Beau Willimon Re-Elected as President of Writers Guild of America East

    Beau Willimon, the playwright and showrunner who launched Netflix’s “House of Cards,” has been re-elected without opposition to a two-year term as president of the Writers Guild of America East. Willimon also ran unopposed in 2017 to succeed Michael Winship. Kathy McGee was elected to the vice president slot over Phil Pilato. Secretary-treasurer Bob Schneider [...]

  • Dickinson First Look Teaser

    TV News: Apple Drops New 'Dickinson' Trailer With Hailee Steinfeld (Watch)

    In today’s roundup, Apple’s “Dickinson” series released a new trailer and Netflix released the trailer for the fifth season of “Peaky Blinders.” DATES The “Cash Cab” revival will come to Bravo on Oct. 7. The game show takes place inside a New York cab, where unsuspecting passengers become contestants in a game of trivia for [...]

  • Jennie Snyder Urman, Katie Wech Team

    Jennie Snyder Urman, Katie Wech Team for Medical Drama in Development at CBS

    CBS is developing a medical drama that hails from writer Katie Wech, Variety has learned. Currently titled “Good Sam,” the series follows a talented yet stifled surgeon who embraces her leadership role after her renowned and pompous boss falls into a coma. When he awakens and wants to resume surgery, however, it falls to her to [...]

  • Jack Gilardi, Longtime ICM Partners Agent,

    Jack Gilardi, Longtime ICM Partners Agent, Dies at 88

    Jack Gilardi, a longtime ICM Partners agent who represented such stars as Burt Reynolds, Sylvester Stallone, Jerry Lewis, Charlton Heston and Shirley MacLaine, died Thursday at his home in Los Angeles. He was 88. Gilardi was known for his gentlemanly style, love of the Los Angeles Dodgers and his skill at representing top actors. He [...]

  • Will Gluck

    Will Gluck Sets TV Overall Deal at eOne (EXCLUSIVE)

    Will Gluck has signed a two-year overall television deal with Entertainment One (eOne), Variety has learned exclusively. Under the deal, Richard Schwartz will continue to oversee all television projects for Gluck’s Olive Bridge Entertainment, with eOne set to serve as studio on all projects under the partnership. “The choice for us was clear given their impeccable [...]

  • Katie Hockmeyer

    NBC Entertainment Names Katie Hockmeyer Exec VP of Late Night Programming

    Katie Hockmeyer has been named executive vice president of late night programming at NBC Entertainment She will report to NBC Entertainment co-chairmen George Cheeks and Paul Telegdy, where she will work on “The Tonight Show Starring Jimmy Fallon,” “Late Night with Seth Meyers,” “Saturday Night Live” and newly launched late-night addition, “A Little Late with [...]

  • Nexstar Completes Tribune Acquisition, Sean Compton

    Nexstar Completes Tribune Acquisition, Sean Compton to Head Programming

    Nexstar Media Group has become the nation’s largest owner of TV stations after completing its $4.1 billion acquisition of Tribune Media. The deal creates a broadcasting colossus with more than 200 stations serving more than 100 markets, although a number of stations will be divested to keep Nexstar in compliance with FCC ownership limits. Nexstar, [...]

More From Our Brands

Access exclusive content