Veteran television director Gail Mancuso will direct the road trip comedy “Besties” for DreamWorks Pictures in her feature film directing debut.

The project has been in the works since last year when DreamWorks picked up the film rights to the script written by Cassie Daniels and Mark Bartosic. Ivan Reitman and Ali Bell are producing with Tom Pollock as executive producer.

The story follows a woman as she embarks on an epic road trip with her best friends to break up the wedding of her childhood crush after discovering a long-lost love note.

Universal would distribute. The project is eyeing a late 2017 start.

Mancuso is a back-to-back Emmy winner for “Modern Family” in 2013 and 2014. She has directed over 300 television episodes, including “Modern Family,” “30 Rock,” “Friends,” and “Roseanne.” Mancuso has also received three DGA nominations for directorial achievement in a comedy series.

Bartosic was a wide receiver for the NFL’s Philadelphia Eagles before breaking into acting a decade ago. Daniels is a writer and stand-up comedian.

Mancuso is represented by ICM Partners and law firm Stone, Genow, Smelkinson, Binder & Christopher. Bartosic and Daniels are repped by Paradigm.