“Grey’s Anatomy” alum T.R. Knight is returning to ABC for a role in Meaghan Oppenheimer’s untitled drama pilot, Variety has learned.

The drama, executive produced by Reese Witherspoon and Bruna Papandrea through their Pacific Standard banner, centers around a ruthless Dallas divorce attorney whose life begins to unravel when her emotionally damaged, love-addicted sister resurfaces, triggering self-destructive tendencies and exposing long-hidden family secrets.

Knight plays Mark, the work nemesis of lead character Gemma, who is competing with her for the same position. On the outside he’s a jolly and likeable guy, but really he’s calculated backstabber you don’t see coming.

The project hails from ABC Studios. “We Are Your Friends” scribe Oppenheimer is co-executive producing.

Knight is currently starring in Hulu’s “11.22.63” alongside James Franco and Sarah Gadon. He was most recently seen on Broadway alongside Nathan Lane, Matthew Broderick and F. Murray Abraham in “It’s Only a Play,” appeared in the feature film “42” opposite Harrison Ford, and had a memorable guest arc on CBS legal drama “The Good Wife.”

Knight was nominated for an Emmy award for his role as George O’Malley in the Shonda Rhimes-produced “Grey’s Anatomy,” and exited the series after Season 5 in 2009. His character had a memorably gruesome exit after jumping in front of a bus to save a woman’s life, an accident that left him unrecognizable to his colleagues. The series, currently in its 12th season, is still going strong as part of ABC’s “TGIT” Thursday lineup.

He is repped by Ashley Franklin at Thruline and Rhonda Price at Gersh.