Eli Jorne has exited Fox’s upcoming comedy “Son of Zorn,” Variety has confirmed.

The live-action and animated hybrid series landed a straight-to-series order for the 2016-17 season, after being developed off-cycle. Jason Sudeikis will voice the lead character.

Jorne’s departure will not have an impact on “Son of Zorn” production and the show is still on track for the upcoming TV season with insiders telling Variety the project is a hot favorite among Fox execs.

Jorne is exiting over creative differences. He created “Son of Zorn” with his former “Wilfred” co-showrunner Reed Agnew. The duo was originally set as co-showrunners on the series, before Sally McKenna came in when Agnew stepped down as co-showrunner, remaining as an exec producer on the show. For now, McKenna will take on sole showrunner duties and exec produce alongside Agnew, Chris Miller and Phil Lord (“Last Man on Earth”), Seth Cohen and Eric Appel.

Upon arriving home on Earth for the first time in 10 years, Zorn (voiced by Sudeikis), a fully animated, legendary warrior, discovers that reconnecting with his live-action son, Alan (Johnny Pemberton, “21 Jump Street”), and his ex-wife, Edie (Cheryl Hines, “Curb Your Enthusiasm”), while suffering through a mundane office job and the banality of suburban life, is harder than waging war in his distant homeland of Zephyria. Tim Meadows (“Saturday Night Live”) also stars in the out-of-the-box series.

Jorne’s departure follows a trend that boomed last broadcast season when a slew of showrunners exited series, before they premiered. Last year, NBC’s “Chicago Med,” Fox’s “The Grinder” and ABC’s “Blood & Oil” and “The Catch” all parted ways with showrunners, but still made it on air for the 2015-16 season.