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Stand Up to Cancer” staged its fifth televised fundraising special on Friday at Walt Disney Concert Hall in downtown Los Angeles.

The telefundraiser, which was executive produced by Bradley Cooper, attracted some of the biggest names in Hollywood. The red carpet was graced by A-List celebrities and media personalities that included Cooper, Emma Stone, Tony Hale, Kathy Bates, Mayim Bialik, Marcia Cross, Eric Stonestreet, Tom Hanks, Rita Wilson, Shannen Doherty, and Katie Couric, among many others.

Couric, who is one of the co-founders of the foundation and serves on SU2C’s Council of Founders and Advisors, noted that teamwork and cooperation is essential in finding a cure for the disease.

“I think that collaboration is the key,” said Couric. “I think as we understand more and more how cancer cells behave, we’re going to figure out more and more ways to attack them.”

Couric also stressed the necessity of continuous cancer research.

“It’s such a complicated disease because it’s different in every single biology,” Couric stated. “Some response rates are so short lived because cancer is so intensely wily and it can outwit its fiercest opponent. So we just have to keep figuring out ways to say ‘oh, no you don’t’ to cancer.”

Hale (“Veep”) said he’s lost three close friends to cancer over the years. He also added that events such as the SU2C telecast provide a beacon of hope to those currently battling cancer.

“It’s very jarring when that happens,” said Hale. “Being here to see the hope, see the encouragement, and to see the headway that is happening in research brings light to [my personal experiences].”

Some celebrities  have been with the foundation since its conception in 2008. For others, like Bates, it’s their first year participating.

“This is actually my first time [at SU2C],” said Bates. “I met [co-founder] Sherry Lansing a couple of years ago, and I was actually asking her advice how to create something like this. But when I see what they’ve accomplished in the last eight years, it’s just awe-inspiring.”

The Stand Up 2 Cancer telecast serves as one of the biggest televised fundraisers in the country. ABC, CBS, FOX, and NBC, along with American Forces Network, ASPiRE, AUDIENCE Network, Bloomberg TV, Bravo, Comedy Central, Discovery Life, E! Entertainment, EPIX, ESPNEWS, FM, FS2, Fusion, FXM, Great American Country, HBO, HLN, ION Television, LMN, Logo, MLB Network, National Geographic, Pivot, RLTV, SHOWTIME, Smithsonian Channel, STARZ, STARZ ENCORE, TBS, Tr3s, VH1, and WGN America are donating one hour of simultaneous commercial-free primetime for the show. The telecast will also begin streaming on Hulu on Saturday.