Rene Angelil, the husband and former manager of Celine Dion, died of throat cancer on Thursday at his Las Vegas home, Dion announced on her Facebook page. He was 73.

Born in Montreal, Angelil’s decades-long music career launched in the 1960s when he formed the pop rock group “The Baronets” with two childhood friends. After the band’s dissolution, he started managing music talent.

In 1981, a then 12-year-old Dion submitted a demo tape to Angelil, who later agreed to manage the budding songstress. The pair, who began dating when Dion was 19, dated for nearly five years before Dion publicly announced their relationship in the album notes of her 1993 studio album “The Colour of My Love.”

The two married in 1994. Angelil appeared alongside Dion in her 2010 concert documentary “Celine Dion: Through the Eyes of the World.”

Following Angelil’s 1999 throat cancer diagnosis, Dion decided to take a break from the limelight to care for him. Still battling cancer, Angelil stepped down as Dion’s manager after 30 years in June 2014 to focus on his health. Not long after, Dion announced another brief retirement from her singing career.

Dion resumed her residency at Las Vegas’ Caesars Palace in August 2015.

“Rene really gave me a gift,” she told USA Today in an August 2015 interview. “When it hits me, it’s going to hit me. But my biggest job is to tell my husband, we’re fine. I’ll take care of our kids. You’ll watch us from another spot.”

Angelil is survived by Dion and his six children.