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Pacific Standard partners Reese Witherspoon and Bruna Papandrea are ending their partnership and going their separate ways.

Papandrea will start a new venture, while Witherspoon stays on as Pacific Standard’s main principle. The duo launched Pacific Standard in 2012, producing “Gone Girl,” “Wild,” and “Hot Pursuit,” with Witherspoon starring in the latter two films. “Gone Girl” was one of the first and highest-grossing films to be produced under the banner, earning an Oscar nomination for star Rosamund Pike and hauling $369 million worldwide.

The pair championed female-driven properties and movie adaptations of bestselling books.

Witherspoon nabbed a best actress Oscar nomination for the adventure drama “Wild,” while costar Laura Dern earned a best supporting actress nom.

Witherspoon and Papandrea will continue to produce the projects they currently have in development, including “Luckiest Girl Alive” at Lionsgate/Summit, “All Is Not Forgotten” at Warner Bros., “Ashley’s War” at Fox 2000, and the Barbie origins movie “Barbie and Ruth.”

They also have the upcoming HBO miniseries “Big Little Lies,” which stars Witherspoon, Dern, Nicole Kidman, Shailene Woodley, and Zoe Kravitz. They will continue to work together under Pacific Standard’s overall deal at ABC, which includes the series “Broken” starring Anna Paquin.

“I’m very proud of the projects that Bruna and I have produced together,” Witherspoon said a statement. “Bruna is a hard-working, extremely talented producer. I’m happy to further collaborate with her on the strong slate of Pacific Standard properties.”