Open Road Pictures has acquired all North American rights to the romantic comedy “Home Again,” starring Reese Witherspoon.

The film will be the directorial debut of Hallie Meyers-Shyer, the daughter of Nancy Meyers who is on board to produce. Meyers-Shyer also wrote the script and Black Bicycle Entertainment’s Erika Olde also financed the film.

Michael Sheen, Nat Wolff and Lake Bell have also joined the cast. Variety first reported Witherspoon’s involvement earlier this year.

“Home Again” is the story of a recently separated mother of two (Witherspoon) whose new life in Los Angeles is overturned when she decides to take in three young, charismatic guys who become part of her unconventional family.

The film is scheduled to begin production in fall of 2016 and is expected to be released in the U.S. in fourth quarter 2017. MadRiver is selling the international rights to the film.

“‘Home Again’ is a funny and sparkling script that will be brought to life by the incomparable Reese Witherspoon,” stated Open Road CEO Tom Ortenberg. “Nancy Meyers has brought audiences some of their all-time favorites and has a proven track record at the box office. We are proud to be in business with this family and the entire team.”

The deal was negotiated on behalf of Open Road Films by Tom Ortenberg, CEO, and Chief Operating Officer and General Counsel, Elliott Kleinberg. CAA negotiated on behalf of the filmmakers.

Meyers-Shyer is represented by WME. Witherspoon, Meyers, Black Bicycle, and Wolff are represented by CAA; Sheen by ICM and Bell by UTA.