Bleecker Street and Participant Media have nabbed North American rights to “Breathe,” an inspirational true-life medical drama that will be directed by Andy Serkis.

The film will star “The Amazing Spider-Man’s” Andrew Garfield as Robin Cavendish, a man who is paralyzed from the neck down by polio, and Claire Foy, who recently turned heads in “Wolf Hall,” as his devoted wife. Instead of yielding to the devastating diagnosis, they travel the world together, campaigning for people with disabilities. Hugh Bonneville (“Downtown Abbey”) and Tom Hollander (“The Night Manager”) will co-star.

The film has other top talent attached, including William Nicholson, the “Shadowlands” screenwriter, and cinematographer Robert Richardson, who has shot the likes of “JFK” and “Hugo.”

Bleecker Street had a nice pick-up out of last year’s Toronto, grabbing “Eye in the Sky,” and seeing the drone thriller emerge as one of the biggest hits of the spring. Participant has a number of films at this year’s festival, including “A Monster Calls” and “Deepwater Horizon.” The two companies partnered on “Denial,” a drama about a Holocaust denier that will have its world premiere at Toronto.

Garfield may have retired Spider-Man’s spandex, but he has been earning raves for his work in the World War II drama “Hacksaw Ridge.”

The acquisition of “Breathe” was negotiated by Kent Sanderson and Avy Eschenasy on behalf of Bleecker Street, Jonathan King and Gabriel Brakin for Participant Media, and Embankment’s Tim Haslam on behalf of Imaginarium.