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George Clooney has signed on to host Hollywood’s Night Under the Stars, an evening of performances celebrating the Motion Picture & Television Fund’s 95th year of helping Hollywood entertainers.

Also appearing at the event will be Matt Bomer, Yvette Nicole Brown, Michael Douglas, Derek Hough, Hugh Jackman, Norm Lewis, Jane Lynch, Johnny Mathis, Sheryl Lee Ralph, Anika Noni Rose, and Catherine Zeta-Jones.

Chaired by Ann and Jim Gianopulos, the event takes place Oct. 1 at the MPTF’s Wasserman Campus in Woodland Hills, Calif.  Ticket sales via the MPTF website will benefit the foundation.

“We are thrilled that our show director Richard Jay-Alexander, who just co-directed the incredible multi-city Barbra Streisand concert tour this month, is putting together a dynamic celebration of 95 years of entertainment and the people who made the magic happen,” said Ken Scherer, CEO of the MPTF Foundation.

Jay Landers will produce the evening, with Emmy-winner William Ross as musical director, conducting a 17-piece orchestra.

Sponsors of the celebration include AARP Foundation, American Express, Delta Air Lines and Target.