Susan Sarandon is headed to the smallscreen.

The Oscar winner will make her starring debut on TV opposite Nick Nolte in Epix’s first original comedy, “Graves.”

Sarandon will play Margaret Graves, the wife of Nolte’s character, a former U.S. president. She begins to pursue her own political ambitions when her husband decides to right the wrongs of his administration, 20 years after leaving office.

This marks the second project in which Nolte and Sarandon have played a married couple, following the 1992 true-life drama “Lorenzo’s Oil.”

“We are overjoyed to have Susan join the cast of Graves,” Epix president and CEO Mark S. Greenberg said in a statement. “Susan is a phenomenal actor whose comedic talents will bring a depth and richness of character to the role.”

Series creator Joshua Michael Stern will write and exec produce the 10-episode show, in addition to directing select episodes. Greg Shapiro, Keith Eisner and Eric Weinberg will also exec produce.

The series, from Lionsgate, is scheduled to begin production this fall. It will premiere on Epix in fall 2016.

Sarandon is represented by UTA.