Mark and Jay Duplass have signed an overall deal with HBOVariety has learned.

The two-year pact follows the renewal for their HBO comedy “Togetherness,” which is set to bow with its second season in 2016, and the pickup of their animated series “Animals,” which was handed a two-season order at the pay cabler.

The proven talent and innate creativity of the Duplass brothers are, for us, pure gold,” Michael Lombardo, HBO president of programming, announced Tuesday. “We are thrilled to have this exclusive opportunity to share their comic genius with the HBO audience.”

The duo commented, “We really share a vision for the new ways TV can be made and have found the perfect partner to do that with, in HBO, especially with the broadening scope of their new HBO NOW service.”

Under the new deal, the Duplass brothers will develop and produce series for HBO by way of their Duplass Brothers Television production arm, which falls under their Duplass Brothers Productions banner. Stephanie Langhoff, president of Duplass Brothers Productions, will also be at the helm of Duplass Brothers Television.

The pair serve as exec producers on “Animals,” which was created by New York-based advertising creatives Phil Matarese and Mike Luciano as a series of animated shorts revolving around downtrodden creatures — pigeons, rats, bedbugs — living in NYC. The animated series, hailing from Duplass Bros. TV, generated buzz after screening at Sundance this year, and is set to debut in 2016.

The Duplass brothers are repped by ICM Partners and Sloane Offer.