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Dianne Wiest and Zoe Lister Jones have been cast in CBS’ comedy pilot “Life in Pieces,” Variety has learned.

Wiest and Jones join Colin Hanks and Betsy Brandt, who were previously cast in the ensemble sitcom, hailing from Kapital Entertainment and Twentieth Century Fox TV, which reunites Jones with “Friends With Better Lives” exec producer Aaron Kaplan.

The single-cam comedy tells the story of one family from the perspective of its different members. Wiest will play the family matriarch, Joan Short, who adores her family and would do absolutely anything for them — as long as she agrees with it. Jones has been cast as Wiest’s onscreen daughter-in-law and Hanks’ wife Jen, a woman used to being in control, who now has a baby and finds out for the first time that she’s not.

Brandt and Hanks will play two of Wiest’s three TV kids, oldest and youngest, respectively. The third, middle sibling is yet to be cast.

The “Life in Pieces” pilot was written by Justin Adler, who will also serve as an exec producer with Kaplan.

Wiest is repped by ICM Partners. Jones is repped by WME and Jackoway Tyerman Wertheimer Austen Mandelbaum Morris & Klein.