Nicole Kidman will return to the West End this fall in the U.K. premiere of “Photograph 51,” Anna Ziegler’s play about the female scientist who had a crucial role in the discovery of DNA.

Michael Grandage directs the production in the latest offering from his Michael Grandage Company, the commercial producing firm that presented a well-received West End season in 2013-14. That lineup included Daniel Radcliffe in “The Cripple of Inishmaan,” which went on to play Broadway.

In “Photograph 51” Kidman will play Rosalind Franklin, the ambitious woman whose contributions to science’s understanding of the building blocks of life are often overlooked. Her prior stage credits include “The Blue Room,” which originated at London’s Donmar Warehouse before it ran on Broadway. She and Grandage recently worked together on Grandage’s upcoming film “Genius.”

Written by American playwright Ziegler, “Photograph 51” was commissioned by a Maryland theater and went on to win a 2008 prize for scripts about science and technology. Ensemble Studio Theater produced it in New York in 2011.

As with Grandage’s prior season of work, “Photograph 51” arrives on the West End with a ticket access initiative that keeps blocks of tickets down at affordable prices. During the run, some 25%, or more than 20,000 tickets, will be sold for £10 (about $15).

“Photograph 51” will run Sept. 5-Nov. 21 at the Noel Coward Theater, which also was home to the titles in Grandage’s previous season. The rest of the cast remains to be set.