Following the success of “Edge of Tomorrow,” Tom Cruise and Doug Liman are now in talks to reteam on the drug-trade pic “Mena.”

Liman has closed a deal to direct. Brian Grazer is producing through his Imagine Entertainment banner along with Quadrant Pictures’ Doug Davison, with Universal distributing.

Pic is based on the spec by Gary Spinelli and follows Barry Seal, a TWA pilot recruited by the CIA to provide reconnaissance on the burgeoning communist threat in Central America. Seal finds himself in charge of one of the biggest covert CIA operations in the history of the U.S., one that spawned the birth of the Medellin cartel and eventually almost brought down the Reagan White House through the Iran Contra scandal.

Cross Creek Pictures will finance “Mena” and Cross Creek’s Brian Oliver and Tyler Thompson will produce alongside Grazer and Davison. Kim Roth will exec produce and oversee the project for Imagine with senior VP of production Kristin Lowe overseeing for Universal. Jason Seagrave will oversee on behalf of Cross Creek.

Cruise is currently filming “Mission: Impossible 5.” Liman is represented by CAA and Weintraub Tobin, and Cruise is represented by CAA and law firm Greenberg Glusker.

Deadline Hollywood first reported the news.