Supergirl” actress Melissa Benoist and “Outlander” star Sam Heughan are set to co-star in the Screen Gems romantic drama “Oxford.”

The film follows an American Rhodes Scholar (Benoist) who, after arriving at Oxford University, falls for an arrogant teaching assistant (Heughan) who is quietly fighting terminal cancer. When she finds out the reason he is so standoffish, they make the most of each day, traveling the world together.

Allison Burnett penned the script. Temple Hill’s Marty Bowen and Wyck Godfrey are producing. Screen Gems is looking to secure a director before setting the film’s start date.

CBS’ “Supergirl” is one of fall’s most hotly anticipated freshman shows, while Heughan has earned critical acclaim for Starz’s breakout hit “Outlander.”

Film credits for Benoist include “The Longest Ride,” “Whiplash” and the upcoming coming-of-age pic “Low Riders.” She is repped by UTA, Anonymous Content and Frankfurt Kurnit Klein & Selz.

Heughan’s next bigscreen project is indie comedy “When the Starlight Ends,” in which he stars alongside Arabella Oz. Season two of “Outlander” is set to bow on Starz in 2016. The Scottish thesp is repped by UTA and United Agents in the U.K.

The news was first reported by Variety sister publication Deadline.