Jason Mantzoukas is in negotiations to join Will Ferrell and Amy Poehler in the New Line comedy “The House.”

Andrew J. Cohen is making his directorial debut with “The House” from a script he co-wrote with Brendan O’Brien.

Ferrell will play a husband who joins with his neighbors to start an illegal casino in his basement after he and his wife (Poehler) blow their daughter’s college fund.

Ferrell and Adam McKay will produce the comedy through their Gary Sanchez Productions banner, along with Nathan Kahane and Joe Drake of Good Universe and O’Brien. Chris Henchy, Spencer Wong and Jessica Elbaum are exec producing. New Line’s Richard Brener, Michael Disco and Sam Brown are overseeing “The House.”

Mantzoukas is popular among New Line execs, having most recently worked on the comedy “How to Be Single,” and the studio sees this as perfect opportunity to team him with two of Hollywood’s top comedic talents.

Mantzoukas broke onto the scene in 2012 opposite Sacha Baron Cohen in “The Dictator” and since then has continued to grab juicy supporting roles in pics like “Baby Mama,” “Neighbors” and “They Came Together” before a major role in the upcoming “Dirty Grandpa” opposite Zac Efron.

He also is a favorite among fans of the FXX show “The League” as the lovable psychopath Rafi.

He can be seen next in the IFC comedy “Sleeping With Other People.” He is repped by UTA and Mosaic.