Diane Kruger, Norman Reedus, Lena Dunham and Gilles Lellouche will star in “Sky,” a drama-come-road-movie that unfolds across the U.S. from French helmer Fabienne Berthaud (“Lily Sometimes”).

The English-language pic is produced by Bertrand Faivre’s Le Bureau, based in Paris, with Germany’s Pandora.

The Bureau Sales, the Bureau’s recently launched unit spearheaded by Rym Hachimi and Emmanuelle Le Courtois, will begin shopping the project in Berlin.

Kruger stars as Romy, who goes with her husband (Lellouche) on a trip to California and accidentally kills him during a violent fight. She flees the scene and embarks on a life-changing solo trip across California and Nevada.

“As with Fabienne Berthaud’s previous films, ‘Sky’ is character-driven and has multiple layers: It’s a film about this woman emancipating herself,” said Le Courtois, who recently joined the Bureau Sales after working at Wide Management and the Coproduction Office.

Haut et Court will release “Sky” in France.

The international cast is completed by Q’orianka Kilcher (“The New World”).

Pic, which is now shooting, marks Berthaud’s third feature film. Her latest film, “Lily Sometimes,” played at Directors’ Fortnight in 2010.

Other highlights on Le Bureau Sales’ Berlin roster include Tessa Morgan’s “The Pioneers,” a documentary film that sheds light on the urban subculture that emerged in 1970s from minority communities living the Bronx, N.Y., South Central L.A., as well as the Manila slums and Brazilian favelas.