Spanish dark comedy maestro Alex de la Iglesia, whose “My Big Night” receives its European premiere Sunday at San Sebastian, is producing “Pieles” (“Skins”), Spanish actor Eduardo Casanova’s feature helming debut.

De la Iglesia’s new Madrid-based outfit Pokeepsie Films produces in partnership with Kiko Martinez’s Nadie Es Perfecto and The Other Side Films.

A newly-minted social drama, close to the American underground tradition, “Skins” tells the story of physically different people marginalized by the society, with characters such as Samantha, a woman with an upside-down digestive system, or Laura, a girl without eyes.

“’Skins’ is a risky, provocative film and, above all, a committed film that speaks us about the social exclusion faced by physically different people,” Alex de la Iglesia told Variety.

He added: “This is told from a explicit and polemical point of view, not because of the desire to create one, but because we believe that it is necessary to be clear with taboo topics. And for an author with Eduardo Casanova’s creativity, it is a must.”

Now in pre-production, “Skins” will roll November-December in Spain, with a Spanish cast led by Macarena Gomez (“Shrew’s Nest”), Carmen Machi (“Spanish Affair”), Secun de la Rosa (“Pancho”), Ana Polvorosa (“My Big Night”), Antonia San Juan (“All About My Mother”) and Jon Kortajarena (“A Single Man”).

Jointly launched by Alex de la Iglesia and actress Carolina Bang, Pokeepsie Films aims to nurture new talent who enjoy fantastic, suspense and terror genres using a different way of telling stories.

Pokeepsie’s first feature film, Esteban Roel and Juan Fernando Andres’ ’50 Spain-set horror meller “Shrew’s Nest,” was distributed in Spain by Sony Pictures Releasing Espana and widely sold abroad by Film Factory Entertainment.

Black comedy “My Big Night,” another Film Factory pickup, screens out of competition as part of San Sebastian’s Official Selection after world preeming Sept. 11 at the Toronto Film Festival.

Starring pop music icon Raphael and a Who’s Who Spanish cast, “My Big Night,” produced by Enrique Cerezo and Telefonica Studios, will hit Spanish theaters Oct. 23, distributed by Universal Pictures International Spain.