After playing the humanoid Cylon Number Six in the iconic series “Battlestar Galactica,” Tricia Helfer returns to Syfy to star in the network’s six-hour event series “Ascension.”

The show centers on the passengers aboard the starship Ascension who were part of a 1963 covert space mission. They now find themselves approaching the point of no return 50 years into their voyage. To top it all off, a young woman has been mysteriously murdered, causing them to question the true nature of their mission.

Helfer will play the manipulative Viondra Denniger, the wife of the ship’s captain, in the drama series created and penned by Philip Levens.

She most recently toplined ABC’s Sofia Vergara exec-produced “Killer Women” and previously starred in Jerry Bruckheimer’s “Dark Blue” for TNT, in addition to guest stints on “Chuck,” “Lie To Me” and “Franklin and Bash.”

Levens will also serve as an exec producer on the series, which will be produced in Montreal by Sea to Sky Studios in association with Blumhouse Prods. Jason Blum and Mark Stern are also exec producers along with Ivan Fecan, Tim Gamble and Brett Burlock.

“Ascension” will be co-financed and distributed by Universal Cable Productions and Lionsgate Television. It’s slated to air from November to December.