Universal’s R-rated comedy “Neighbors” has launched respectably in latenight shows Thursday with $2.56 million at 2,224 locations in the U.S.

“Neighbors,” starring Seth Rogen and Zac Efron, is on track to rival the second weekend of Sony’s “The Amazing Spider-Man 2” with a potential three-day opening in the $35 million to $39 million range.

Advanced ticket sales for “Neighbors” on Fandango have been nearly double last summer’s “This Is the End,” which also starred Rogen and opened with a $20.7 million weekend in the U.S., and the most for an R-rated comedy since Universal’s 2012 hit “Ted.”

“Neighbors” expands to 3,279 theaters Friday following a marketing campaign emphasizing the frat-versus-family plotline. Universal has been gaining traction for “Neighbors” since premiering the movie at South by Southwest in March — a similar strategy employed with its 2011 hit “Bridesmaids.”

“The Amazing Spider-Man 2” opened with $92 million last weekend and has grossed $107 million in its first six days in the U.S.  A drop in the 50% to 50% range for its second frame would land the tentpole in the $42 million to $45 million range.

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