Newcomer “The Other Woman” has knocked “Captain America: The Winter Soldier” off its throne after a three-week rule.

Fox’s revenge comedy opened Stateside to $9.3 million on Friday, dominating Disney-Marvel’s superhero pic, which earned $4.5 million. “The Other Woman” is on track for $25 million and “Captain America” will likely draw $15 million-plus.

While the “Captain America” sequel was runner-up on Friday, the blockbuster may come in third in the weekend race as “Heaven Is for Real” poses a real threat. Sony’s faith-based hit looks to repeat last week’s second-place finish with upwards of $15.4 million. Studio projections, however, are more modest at $13 million to $14 million.

The femme-driven, female-skewing “Other Woman” from director Nick Cassavetes has been benefiting from positive word-of-mouth. Although it was mostly panned by critics (24% fresh on Rotten Tomatoes), the raunchy girl power pic is performing well partly thanks to its three leading ladies: Cameron Diaz, Kate Upton and Leslie Mann. In the movie, the women team up to get payback on the Don Juan that’s three-timing each of them.

Diaz, who also worked with Cassavetes on 2009’s “My Sister’s Keeper,” has found her footing with recent edgy roles, including “The Counselor” and “Bad Teacher.” The latter opened to $31.6 million in 2011.

“Other Woman”, which cost $40 million to produce, opened last week in Australia opposite “The Amazing Spider-Man 2” with $4.2 million and expanded to 28 other markets this weekend (the U.K. being the only major territory). The pic is showing in 3,205 U.S. theaters.

Meanwhile, “Captain America’s” box office hot streak has fizzled after three consecutive wins. If it had stayed on top, the Chris Evans-starrer would have been in impressive company with 2012’s “Hunger Games” and 2008’s “The Dark Knight,” which recently had four-peats.

The superhero sequel has not only passed the $200 million mark domestically, but overlapped its predecessor, “The First Avenger,” which hauled in $176.7 million Stateside in its lifetime, in half a month.

“Heaven Is for Real” made $4 million on Friday. The Christian drama, which cost just $12 million to produce, is hot on the heels of “Captain America” and could overtake the $170 million tentpole. The pic is showing exceptional staying power, down about 30% from last weekend.

This year’s latest faith-based offering, based on Todd Burpo’s 2010 bestseller of the same name, has a religious core, but also struck a cord with mainstream audiences.

Relativity Media’s Paul Walker-starrer “Brick Mansions” (B+ CinemaScore) also opened this weekend in 2,642 theaters. The actioner — an English-language reboot of the French film “Banlieue 13” — grossed $3.6 million on Friday for a fourth place finish. It’s on track for a modest $9 million to $10 million weekend launch.

“Brick Mansions,” which EuropaCorp and Transfilm International produced for $28 million, is the first release to star Walker following his death late last year. The pic is Walker’s last completed role; he was taking a break from shooting “Fast & Furious 7” at the time of the car accident over Thanksgiving weekend.

Relativity worked closely with Walker’s family during the marketing process. The distributor made a donation, including the cost of the film’s world premiere, to Walker’s charity Reach Out WorldWide.

“Brick Mansions” marks the directorial debut for editor Camille Delamarre (“Taken 2”) and also stars David Belle, who is reprising his role from the original 2004 film, and rapper RZA.

The film, which grossed $400,000 during Thursday night screenings, played strongly among African American and Latino audiences.

Fox’s “Rio 2” placed fifth on Friday with $3.3 million, raising its three-week cume to $85.8 million. The 3D animated pic will likely reel in $13.6 million this weekend for a fourth-place finish.

This weekend’s third wide release, Lionsgate’s “The Quiet Ones,” lived up to its name with a $1.5 million launch in 2,027 locations on Friday. The horror pic is en route to earn $3.6 million by Sunday.

John Pogue’s “Quiet Ones” starring Jared Harris and Sam Clafin tells the story of a university professor and his students who perform experiments on a young woman.

Meanwhile, Warner Bros.’ “Transcendence” was unable to redeem itself after flopping last weekend. The Johnny Depp-starrer earned $1.3 million on Friday. It looks to fall about 60% to gross $4 million this weekend.