USA Network has set a March 6 premiere for its first original comedy series in years, the Denis Leary-produced “Sirens.”

The series about three emergency medical technicians in Chicago will bow at 10 p.m. following the third-season premiere of dramedy “Suits.”

Seeding a comedy block is a big priority for the top-rated basic cabler, which has invested big bucks in the off-network rights to “Modern Family.”

In addition to “Sirens,” USA has the greenlit comedy series “Playing House” on the bench awaiting a premiere date. And the cabler at present is sorting through four completed comedy pilots with the intention of ordering at least two more series.

“Sirens” stars Michael Mosley, Kevin Bigley and Kevin Daniels as EMT’s with “unruly” personal lives. Pilot for the Fox TV Studios series, based on a U.K. format, was co-written by Leary and Bob Fisher.

“Sirens” will open with two back-to-back episodes. The following week, the show’s 10:30 p.m. lead-out will be a “Modern Family” seg.

“As a top cable drama, ‘Suits’ has a huge following of young viewers making it a perfect segue to Denis Leary and Bob Fisher’s brand of comedy,” said Jackie de Crinis, USA’s exec veep of original programming. “Both series feature sharp, witty banter from an ensemble of great characters.”

USA also has set a Jan. 8 premiere for the eighth season of “Psych,” and a Jan. 9 debut for season five of “White Collar.”