The days of Ginger, Sporty and Posh may be long gone, but another pack of five spicy women were serving up the girl power at the June 27 Hollywood premiere of “The Hot Flashes.”

“I worked with a few good men on this project, but I worked with a lot of great women,” said scribe Brad Hennig, “and tonight is all about the ladies.”

The Vertical Entertainment pic stars Brooke Shields, Daryl Hannah, Virginia Madsen, Camryn Manheim and Wanda Sykes as a ragtag pack of middle-aged women who help raise money for a dwindling mobile mammography unit.

The preem screened at the Arclight Hollywood and was followed by a benefit for the American Cancer Society, at nearby Lure.

Helmer Susan Seidelman says the pic fills a considerable gap in offerings for mature auds, with five parts for women over 45 — without the descriptions of Mom or Grandma.

On the pink carpet, thesps echoed each other’s sentiments of instant camaraderie while shooting; Madsen called the premiere a reunion of a sisterhood. From group texts to Mardi Gras to boozy karaoke, the five stars formed a quick bond on and off camera. Manheim recalled late night chats at NOLA’s Bridge Lounge.

“We’d talk about our relationships, about getting older, about motherhood, about filler and Botox,” she said.

Sykes clarified: “If there’s drinking involved, we get down to it.”

A femme project from top to bottom, pic was funded almost exclusively by female investors, most of whom were first-timers from the Silicon Valley. But with Hennig’s script at its core, “The Hot Flashes” doesn’t leave a gender gap.

“This isn’t a male or female issue,” Shields noted. “Whether it’s breast cancer or prostate cancer, we’re all unified in the fact that it’s indiscriminate.”

Hennig (who also produced) penned the flick as a tribute to his late mother, who died from breast cancer. A cancer survivor herself, producer Nina Henderson Moore was also drawn to the project because of a personal connection to the cause.

“My mom had a double mastectomy four days before we started shooting,” she said. “She’s a breast cancer survivor now. The film empowered me to get through it with her. Everyone on the project has some connection to it.”