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James Franco Locks in Broadway Debut in ‘Of Mice and Men’

Actor will star with Chris O'Dowd in a new production of the John Steinbeck tale

James Franco’s long-gestating Broadway bow in “Of Mice and Men” has at last set a theater and dates, with the thesp starring opposite Chris O’Dowd in a production set to begin previews at the Longacre Theater in March.

Lead producer David Binder has been working to pull together a new staging of the 1937 play version of the John Steinbeck novel for a while now, and Franco has seemed a likely leading man since he mentioned the project on “The Colbert Report” back in March.

Slot for the show has become available now that Rialto real estate has opened up at the Longacre, where tuner “First Date,” which has never lit up the box office, recently announced it would shutter Jan. 5.

Franco will play George, the itinerant ranch worker on the hunt for opportunities with Lennie, the mentally limited man to be played by O’Dowd (“Bridesmaids,” “Family Tree”), also making his Broadway debut. Anna D. Shapiro, who picked up a Tony for her direction of “August: Osage County,” directs.

Revival of the play, the first to land on the Main Stem since 1974, is produced by Binder along with Kate Lear, Darren Bagert, Adam Zotovich, Barbara Whitman and Latitude Link. 101 Prods. is on board as executive producer.

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Franco marks the latest high-profile Hollywood name to give Broadway a try, and pairing a familiar face with a familiar title is one of the most reliably profitable financial models on the Rialto. Still, few stars have the sales muscle to pull in huge numbers a la Daniel Craig in the current revival of “Betrayal,” and it remains to be seen just how big Franco’s draw at the Broadway box office will be.

“Of Mice and Men” starts previews March 19 ahead of an April 16 opening, joining a spring slate of Main Stem plays that also includes Denzel Washington starrer “A Raisin in the Sun.”

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