In her first role depicting a real-life individual, Uma Thurman has been tapped to play Anita Bryant in the biopic “Anita.”

Rob Epstein and Jeffrey Friedman, whose latest pic “Lovelace” premiered in Sundance, will co-direct from a screenplay by Chad Hodge. Darren Star, Howard Rosenman, Jeffrey Schwarz and Dennis Erdman produce.

Based on the true story, the film will follow former celebrity singer and orange juice spokeswoman Anita Bryant, who after allowing a gay screenwriter into her home, is forced to confront her past as an anti-gay Christian crusader who successfully campaigned to overturn a gay rights law in Florida and destroyed her show biz career in the process.

UTA Independent Film Group and WME are co-representing domestic rights.

Thurman, who is repped by UTA and Untitled Entertainment, can be seen next in Lars von Trier’s “Nymphomaniac.”