Genesis Rodriguez is in final negotiations for the female lead in Kevin Smith’s horror pic “Tusk.”

Smith will write and direct, with Justin Long and Michael Parks also starring.

Story follows a podcaster who sets out to interview an eccentric, reclusive old seafarer, only to find himself a plaything in the gruesome plot of a deranged killer.

Demarest Films will finance and produce. Demarest’s Sam Englebardt and William D. Johnson will produce alongside Shannon McIntosh for Smith’s Smodcast Pictures banner. Demarest’s David Greathouse and Jennifer Schwalbach are exec producers.

Production is set to start next month.

Rodriguez is currently shooting WB’s “Run All Night.” She is repped by CAA and manager Ivan de Paz.