No stranger to putting on a big party, “Wedding Crashers” helmer David Dobkin looks ready to take aim at one of the great hosts of our time.

Dobkin is in talks to direct Warner Bros.’ untitled biopic about Hugh Hefner, the bon vivant and mogul who founded Playboy magazine in 1953 and built the magazine into a media empire while cultivating a reputation as a swinging bachelor well into his ’80s.

“Rush” screenwriter Peter Morgan is writing the film, returning to a similar era as seen in his 2008 “Frost/Nixon.”

Jerry Weintraub is on board to produce the untitled drama. Lynn Harris will oversee for the studio.

The Hugh Hefner project was originally set up at Universal with Imagine Entertainment producing, but it never coalesced to their satisfaction and the film was put into turnaround.

Dobkin’s commitment gives “Hefner” some serious momentum, and the studio will now look for the right actor to don Hefner’s silk pajamas. Robert Downey Jr. and Hugh Jackman were originally courted for the part at Universal, and Warners will likely look for an actor with similar charm and wit.

The WME-repped Dobkin is known for comedies like “Wedding Crashers” and “The Change-Up” but recently wrapped production on dramedy “The Judge” with Downey Jr.  The fact that “Hefner” has both dramatic and comedic elements may have helped get Dobkin the job.