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NBC will keep the clock ticking 24 hours a day for 12 days straight with “The Million Second Quiz,” a stress-inducing combo reality-trivia competition show aimed at engaging audiences on TV and online.

Series, set to bow this fall in primetime, will broadcast live from a “gigantic hourglass-shaped structure” in Manhattan, which will also be home to the players who remain in the game the longest, as other contestants try to boot them out. The Peacock is promising ultimate champ could claim $10 million cash prize.

Skein is “a genre-redefining spectacle,” said Paul Telegdy, prexy of alternative and latenight programming for NBC Entertainment. “It is a game, a social experiment and a live interactive event all wrapped into a uniquely sticky entertainment experience.”

Expect to see some serious sleep deprivation: Contestants will get time every hour to take care of business, “not really enough to sleep but eat, etc.,” NBC rep said.

Viewers who tune in to “The Million Second Quiz” can play at home for a  chance to appear on the live show. NBC affiliates will be able to interact live with contestants throughout the day and during the primetime show to be part of the action and showcase local contestants from their area.

“The Million Second Quiz” will be produced by All3 Media America, Studio Lambert and Universal TelevisionStephen Lambert (creator of “Wife Swap,” “Undercover Boss” and other skeins), Eli Holzman and David Hurwitz serve as exec producers.