Fox is pairing up its new tooth fairy, Larry the Cable Guy, with the National Children’s Oral Health Foundation as a way to promote its direct-to-homevideo sequel “Tooth Fairy 2.”

The comedian, who also serves at the voice of Mater in Disney’s “Cars” franchise, will star in a public service announcement for the non-profit and its marketing materials leading up to the release of the pic on DVD and Blu-ray, March 6.

The NCOHF, also known as America’s ToothFairy, teaches children the importance of good oral health care.

Twentieth Century Fox Home Entertainment will debut the PSA to dental health professionals at the America’s ToothFairy Celebration of Smiles event Feb. 23 at the Chicago Hyatt Regency-McCormick Place, with Larry the Cable Guy and co-star Brady Reiter in attendance. Together, they will launch the America’s ToothFairy Kids Club.

“Tooth Fairy 2” is the first pic the NCOHF has supported.

“We always look for partnerships that can help complement and expand the story of our projects,” said Mary Daily, prexy and chief marketing officer of worldwide marketing, Twentieth Century Fox Home Entertainment. “Larry the Cable Guy as the Tooth Fairy lends itself to great family fun and partnering with the National Children’s Oral Health Foundation is a perfect fit.”

In “Tooth Fairy 2,” Larry the Cable Guy is sentenced to become a Tooth Fairy after telling a child that the character is a myth. First “Tooth Fairy,” starring Dwayne “The Rock” Johnson, earned $112 million worldwide after its release early 2010.