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The most popular cable series among preschoolers, “Doc McStuffins,” has earned a second-season renewal from Disney Channel and sibling Disney Junior.

“Doc” ranks first with kids 2-5 among cable programs and is the No. 1 show that is targeted at preschoolers in total viewers. A total of 25 episodes have been ordered for the second season, which is scheduled to launch in mid-2013.

“The series is resonating with boys and girls across our demo — kids ages 2-7,” said Disney Junior Worldwide senior veep of original programming and general manager Nancy Kanter. “And we’ve heard that the show, particularly as parents watch with their kids, has opened up a family dialogue about the importance of good health and compassion. Importantly, we are also hearing that the show is helping to take the worry out of going to the doctor that so many young children experience.”

Chris Nee (“Little Bill”) created “Doc” and exec produces for Brown Bag Films in association with Disney Channel, with Norton Virigien (“Rugrats”) directing.