A new production of Neil Simon comedy “The Sunshine Boys,” toplined by Danny DeVito and Richard Griffiths, has locked in a 12-week run on the West End beginning in April.

Thea Sharrock (“Equus”) will helm the production from London-based Sonia Friedman Prods. and American producer Richard Willis (“Priscilla Queen of the Desert,” “Next Fall”). Given the frequent trans-Atlantic transfers with which Friedman is involved, the show seems likely to be considered for a potential shift to Broadway.

Production, which had previously been rumored for a West End slot (Variety, Jan. 30-Feb. 5), moves into the Savoy Theater, the venue soon to be vacated by Friedman’s production of “Legally Blonde.”

DeVito makes his West End debut in “Sunshine” opposite Griffiths, the Brit thesp last on Broadway in Sharrock’s production of “Equus.”

Storyline of Simon’s 1972 play centers on an estranged vaudeville duo who are convinced by CBS to reunite for one last show. Title also spawned a 1975 movie incarnation that starred George Burns and Walter Matthau, as well as a TV version toplined by Woody Allen and Peter Falk.

Show begins previews April 17 ahead of a May 17 opening at the Savoy Theater, where the production will play through July 28.