Nathan Lane’s next Broadway outing, Douglas Carter Beane play “The Nance,” is set for an April opening at the Lyceum Theater.

The Lincoln Center Theater production had been expected to land in a Rialto house sometime in the spring, but no dates or venue had previously been locked in.

Lane is considered one of the Broadway’s most reliable box office draws. “Nance” will rep his first stint on the Main Stem since he toplined “The Addams Family” in 2010; more recently he starred in a Chicago staging of “The Iceman Cometh.”

“Nance” centers on the 1930s burlesque tradition of a campy homosexual character, often played by a straight man. Lane plays a nance actor who’s gay. Play also incorporates burlesque sequences into the story of the man’s exploits onstage and off.

Jack O’Brien helms the show, with a creative team that includes John Lee Beatty (sets), Ann Roth (costumes), Japhy Weideman (lights) and Leon Rothenberg (sound).

“Nance” will be the second Broadway outing for Beane this year following February opener “Cinderella,” the revival of the Rodgers and Hammerstein tuner for which he wrote a new book. O’Brien also has another show on the sked, helming Katie Holmes starrer “Dead Accounts” in a production that opens next month.

“Nance” begins previews March 21 ahead of an April 15 opening at the Lyceum, which hasn’t had a tenant since “Venus in Furs” closed in June. Further casting remains to be set.