“Clybourne Park” is moving into the Broadway neighborhood, opening this spring at the Walter Kerr Theater.

Run marks a return to Gotham for the play, following the show’s Off Broadway’s preem at Playwrights Horizons in 2010.

Pam MacKinnon, who helmed that initial staging as well as the current production at the Mark Taper Forum in L.A., will direct on the Rialto as well. The cast of the West Coast staging — all of whom also appeared in the Playwrights Horizons bow — is expected to move with the show to the Kerr.

Story about the shifting social, economic and racial makeup of a Chicago nabe took home the Pulitzer for drama last year. Since its run Off Broadway, where the show earned strong reviews, “Clybourne” has been produced at a number of regional theaters including Woolly Mammoth in D.C., where the title proved so popular it was brought back for a return run.

New York return of the show will mark the Main Stem debut of writer Bruce Norris (“The Pain and the Itch”).

“Clybourne” steps into the venue vacancy left by short-lived tuner “Lysistrata Jones” when it shuttered Jan. 8. The 2011-12 Broadway season’s lineup of new plays has become increasingly crowded in recent weeks, with “Clybourne” and another recent addition, “Magic/Bird,” joining a slate that already includes “Other Desert Cities,” “Seminar,” “The Mountaintop,” “Stick Fly,” “Chinglish,” “Venus in Fur” and “One Man, Two Guvnors.”

“Clybourne Park” opens on Broadway April 12.