George Clooney will add more luster to his philanthropic record in October when he is feted at the Carousel of Hope gala benefiting research and treatment for childhood diabetes.

Barbara Davis’ biennial fundraiser for her Denver-based Center for Chilhood Diabetes is the glitziest, most elaborate event on Hollywood’s charity calendar. The 26th Carousel of Hope ball, set for Oct. 20 at the Beverly Hilton, is sponsored by Mercedes-Benz, which has backed the past five editions.

Clooney will receive the Brass Ring Award in recognition of his commitment to philanthropy and social causes and his artistic achievements. Aretha Franklin and Kenneth ”Babyface” Edmonds are set to perform. Jay Leno will return as emcee, while George Schlatter and David Foster will be back as producer and musical director, respectively.

Clooney’s long list of good works includes his activism to raise awareness of the humanitarian crisis in Sudan. More recently he’s become a major fundraiser for the Motion Picture and Television Fund.

During the past 35 years, Carousel of Hope events have raised more than $75 million for the center, which provides specialized care for children and adults with type 1 and type 2 diabetes. Davis founded the org with her late husband, Marvin Davis, the Texas oilman and one-time owner of 20th Century Fox.