Zooey Deschanel has signed on as the lead for Fox’s untitled comedy pilot from writer Liz Meriwether.

The single-cam laffer, previously known as “Chicks and Dicks” before Fox gave it a greenlight, is an ensembler that explores the sexual politics of men and women via a woman who moves in with three boorish men.

David Finkel and Brett Baer will be the showrunners; Meriwether (the co-writer of “No Strings Attached”), director Jake Kasdan, Peter Chernin and Katherine Pope also exec produce. Project comes from Chernin Entertainment in association with 20th Century Fox Television.

The casting creates the possibility that Fox will enter the fall with a pair of Deschanel starrers: this one and “Bones,” with Emily Deschanel.