Sitcom, from Universal Media Studios, stars Hank Azaria and Kathryn Hahn as quirky co-workers on the rebound who are attracted to one another.
Leggero, who has a talent holding deal with the Peacock, will play Emma, an opinionated executive assistant.
Leggero most recently worked with the net as a judge on “Last Comic Standing.” She has a Comedy Central standup spesh bowing Friday.
Previous TV appearances include roles on “It’s Always Sunny in Philadelphia,” “The Sarah Silverman Program” and “Samantha Who?”
Leggero is represented by Gersh and managed by Brillstein Entertainment.