Kathleen Turner will get “High” on Broadway this spring, toplining Matthew Lombardo’s play at the Booth Theater in a run that begins in March.

Turner stars as a foul-mouthed nun and recovering alcoholic whose faith is tested when she attempts to help a young drug addict battle his addiction. Evan Jonigkeit, who has appeared with Turner in prior productions of the play, co-stars as the addict, with Stephen Kunken signing on in the role of a priest.

Play reteams scribe Lombardo and helmer Rob Ruggiero, who collaborated on last season’s Broadway outing “Looped.” the short-lived play that starred Valerie Harper as Tallulah Bankhead.

“High” bowed last year in a three-city circuit of regional theaters, preeming in July at TheaterWorks in Hartford, Conn., then going on to Cincinnati Playhouse in the Park and the Repertory Theater of St. Louis. In those incarnations (also directed by Ruggiero), Turner and Jonigkeit appeared with Michael Berresse in the role to be played by Kunken in Gotham.

Broadway staging is produced by Leonard Soloway, Chase Mishkin, Terry Schnuck, Ann Cady Scott, Timothy J. Hampton, James and Catherine Berges, the Shubert Org and the Repertory Theater of St. Louis.

Turner most recently starred on Broadway in the 2005 revival of “Who’s Afraid of Virginia Woolf?,” and also has appeared on the Rialto in “The Graduate,” “Indiscretions” and “Cat on a Hot Tin Roof.” Recent Off Broadway credits include the 2009 production of Charles Busch play “The Third Story” and, as a director, the 2008 Roundabout Theater Company production of “Crimes of the Heart.”

Booth Theater was recently vacated by tuner “Next to Normal,” which shuttered Jan. 16. “High” begins previews there March 25 ahead of an April 19 opening.