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Taking the film’s title a touch too seriously, one audience member at Monday’s premiere of the Weinstein Co.’s “Scream 4” let out yelps continuously during the screening, including, but not limited to, the ringing of doorbells and telephones.

Such enthusiasm was fitting for a pic that received cheers throughout the night, notably when director Wes Craven offered words of comfort just before the lights dimmed at the Chinese Theater. “If you get really afraid, I’ll be in the back,” he offered.

During his opening remarks, TWC co-chairman Bob Weinstein addressed the franchise’s chances of expansion.

“We’d be at ‘Scream 30’ if it was up to Harvey.”

Guests, including Jamie Kennedy, Seth Green and Marilyn Manson, made up the packed house, where the industry crowd snickered loudly when a character expressed sympathy for a dead show bizzer.

The crowd moved down Hollywood Boulevard for an afterparty at the Redbury. At the site of the valet line, however, Manson expressed a quick regret to companion Eli Roth.

“I told you I should have taken my bike!”