Following their biggest opening weekend as studio heads, Universal chairman Adam Fogelson and co-chair Donna Langley have undertaken their biggest exec shuffle since being named studio co-chairs.

Debbie Liebling has exited her post as U prexy of production a day after the studio announced its biggest opening ever with “Fast Five.”

Universal named Peter Cramer and Jeffrey Kirschenbaum co-presidents of production Monday, effective immediately.

“Over the past 18 months, as we refined our process, it became clear that a different structure would better suit our needs going forward,” Fogelson and Langley said in a statement. “The new structure will have a smaller executive team with broader responsibilities. Debbie has been a good leader and strong contributor through this transition period, and we wish her well in her new endeavors.”

Liebling was at 20th Century Fox before she was hired 18 months ago by Fogelson and Langley.

Before his elevation to production co-prexy, Cramer, who has been at U since 2005, served as senior exec VP of production. Kirschenbaum was exec VP of production and has been with the studio since 2001.

Kirschenbaum oversaw the development of “Fast Five,” the most recent installment in the “The Fast and the Furious” franchise.

Liebling joined 20th Century Fox in June 2002. During her tenure she developed and shepherded features including “Borat!” and “Dodgeball: A True Underdog Story.”