The question at Screen Gems’ “Friends With Benefits” premiere in Manhattan was whether guys find it easier to have sex without an emotional commitment than gals.

At the Ziegfeld on Monday, Justin Timberlake offered, “I don’t think I’m going out on a limb saying yes, it’s easier for guys.”

Co-star Mila Kunis, who winged her way to Detroit the next day to continue filming ” Oz, the Great and Powerful” with James Franco, wasn’t so sure. “It’s just as hard for everybody,” she said. “Ultimately it’s either going to upgrade or downgrade.”

Patricia Clarkson — she plays Kunis’ wacky mother — also took the middle road, saying, “It easy for men or women, just depending who you are. It didn’t work for me. I know a lot of people it works for and I think a lot of people are willing to admit now, because it’s not taboo, that they just want the physical.”

Director and co-writer Will Gluck had the last word at the Top of the Standard after-party: “I think it might be easier for men but the only way friends with benefits gets established is for the woman to say yes. Because every man would like friends with benefits with everybody but it’s a woman who has to say, ‘We’ll do it.’?”