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Abigail Breslin is growing up on screen, commiting to topline Beth Schacter’s indie comedy “A Virgin Mary” just weeks after signing on to the adult-themed true crime pic “The Class Project.”

Schacter (“Normal Adolescent Behavior”) wrote “Virgin Mary,” described as a coming-of-age story in the tradition of “Sixteen Candles.”

The 15-year-old Breslin (“Little Miss Sunshine”) will star as a teen who vows to have sex with her best male friend if they’re still virgins by the time they turn 18.

Carter Jenkins (“Valentine’s Day”) will star opposite Breslin, while Keke Palmer (“Akeelah and the Bee”) will play her best friend. Daryl Sabara (“Spy Kids”) is set to co-star.

Black Sheep Entertainment partners Jordana Mollick and Brendan Bragg will produce along with Steakhaus Prods. Cotty Chubb (“Appaloosa”) will exec produce. Production is slated to start early next year.

Breslin next stars opposite Alessandro Nivola in Tribeca Films’ “Janie Jones,” slated to open Oct. 28, and appears in as part of the ensemble of Garry Marshall’s “New Year’s Eve,” which Warners releases Dec. 9.

Palmer has spent the last few years focusing on her career as a recording artist, with Interscope Records set to release her sophomore album. Thesp, who voices Peaches in next summer’s “Ice Age: Continental Drift,” will soon be seen alongside Queen Latifah and Dolly Parton in “Joyful Noise.”

Jenkins recently wrapped the indie “Struck by Lightning,” while Sabara next appears in Disney’s “John Carter.”

Breslin and Palmer are repped by ICM and Untitled Entertainment, while Jenkins is repped by WME and manager Scott Melrose. UTA reps Schacter and Sabara along with Anonymous Content and Untitled, respectively.